4-isocyanato-2-piperidinecarboxylic acid (phenylmethyl) ester
Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate
CAS: 220394-91-2
Molecular Formula: C14H16N2O3
4-isocyanato-2-piperidinecarboxylic acid (phenylmethyl) ester - Names and Identifiers
4-isocyanato-2-piperidinecarboxylic acid (phenylmethyl) ester - Physico-chemical Properties
| Molecular Formula | C14H16N2O3 |
| Molar Mass | 260.29 |
| Density | 1.19g/cm3 |
| Boling Point | 185 °C |
| Flash Point | 189.7°C |
| Vapor Presure | 2.73E-06mmHg at 25°C |
| Refractive Index | 1.576 |
4-isocyanato-2-piperidinecarboxylic acid (phenylmethyl) ester - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2206 |
| Hazard Note | Harmful |
4-isocyanato-2-piperidinecarboxylic acid (phenylmethyl) ester - Introduction
Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate is an organic compound with the chemical formula C12H13NO3S. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
-Melting point: About -8 ℃
-Boiling point: About 156-158 ℃
Use:
- Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate can be used as an intermediate in organic synthesis and can participate in a variety of organic reactions.
-It is widely used in the field of medicine and can be used to synthesize various biologically active compounds.
Method:
Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate has many preparation methods. A commonly used preparation method is as follows:
1. The corresponding benzyl picolinate is reacted with 4-isothiocyanophenylacetic acid under alkaline conditions.
2. When the reaction proceeds, stir at an appropriate temperature and control the reaction time, and improve the yield by controlling the reaction conditions.
3. After the reaction, the generated product was purified by an appropriate method to give Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate.
Safety Information:
- Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate is a chemical and must be used in accordance with safe operating procedures and wear appropriate personal protective equipment.
-Irritating effect on skin and eyes. Rinse with plenty of water immediately when in contact and seek medical help.
-When handling or storing the compound, pay attention to avoid fire and high temperature, and avoid contact with incompatible substances such as oxidants.
-When using or disposing of the compound, comply with local laws and regulations, and pay attention to environmental protection.
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
-Melting point: About -8 ℃
-Boiling point: About 156-158 ℃
Use:
- Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate can be used as an intermediate in organic synthesis and can participate in a variety of organic reactions.
-It is widely used in the field of medicine and can be used to synthesize various biologically active compounds.
Method:
Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate has many preparation methods. A commonly used preparation method is as follows:
1. The corresponding benzyl picolinate is reacted with 4-isothiocyanophenylacetic acid under alkaline conditions.
2. When the reaction proceeds, stir at an appropriate temperature and control the reaction time, and improve the yield by controlling the reaction conditions.
3. After the reaction, the generated product was purified by an appropriate method to give Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate.
Safety Information:
- Benzyl-4-isocyanatotetrahydro-1(2H)-pyridinecarboxylate is a chemical and must be used in accordance with safe operating procedures and wear appropriate personal protective equipment.
-Irritating effect on skin and eyes. Rinse with plenty of water immediately when in contact and seek medical help.
-When handling or storing the compound, pay attention to avoid fire and high temperature, and avoid contact with incompatible substances such as oxidants.
-When using or disposing of the compound, comply with local laws and regulations, and pay attention to environmental protection.
Last Update：2024-04-09 15:17:55
